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expert reaction to phase 3 trial results of lecanemab for early Alzheimer’s...

Results of the phase 3 trial of lecanemab for early Alzheimer’s disease has been published in New England Journal of Medicine (NEJM).   Comments after the CTAD conference presentation of results Prof...

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expert reaction to unpublished abstract comparing donanemab and aducanumab on...

A conference abstract (not a published paper) presented at the Clinical Trials on Alzheimer’s Disease (CTAD) Conference 2022 compares the drugs donanemab and aducanumab on amyloid lowering in early...

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dementia prevention – what does the evidence say about maintaining brain...

The latest evidence suggests that up to 40% of all cases of dementia are linked to factors we may be able to influence ourselves, yet just a third of UK adults think it’s possible for people to reduce...

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expert reaction to observational study on vitamin D supplementation and...

A study published in Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring looks at vitamin D supplementation and dementia.   Dr Rosa Sancho, Head of Research at Alzheimer’s...

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expert reaction to observational study on Mediterranean diet and risk of...

An observational study published in BMC Medicine looks at adherence to a Mediterranean diet and risk of dementia.   Dr Annette Creedon RNutr, Nutrition Manager, British Nutrition Foundation, said:...

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expert reaction to study of elite football players and risk of dementia

A study published in The Lancet Public Health looks at neurodegenerative disease among male elite football players in Sweden.   Prof Huw Williams, Professor of Clinical Neuropsychology, University of...

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expert reaction to observational study looking at hearing aid use and risk of...

An observational study published in The Lancet Public Health looks at hearing aid use and all-cause and cause-specific dementia.   Prof Bart De Strooper, Director of the UK Dementia Research...

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expert reaction to Phase 1b study of MAPTRx in mild Alzheimer’s disease

Results of a phase 1b trial, looking at Tau-targeting antisense oligonucleotide MAPTRx in mild Alzheimer’s disease, has been published in Nature Medicine.   Dr Susan Kohlhaas, Executive Director of...

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expert reaction to statement by Lilly saying that Alzheimer’s drug donanemab...

A press release from Eli Lilly states that their antibody treatment, donanemab, significantly slowed cognitive and functional decline in phase 3 study of early Alzheimer’s disease.   Prof Bart De...

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expert reaction to observational study on HRT and dementia

An observational study published in The BMJ looks at menopausal hormone therapy and dementia.   Dr Anita McGrogan, Senior Lecturer in the Department of Life Sciences at the University of Bath, said:...

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expert reaction to results from Eli Lilly on its anti-amyloid drug donanemab

Results from Eli Lilly’s TRAILBLAZER-ALZ 2 Randomized Clinical Trial looking at the use of donanemab in early symptomatic Alzheimer’s disease has been published in JAMA.   Tara Spires-Jones, President...

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expert reaction to randomised control trial of hearing aids for cognitive...

Results of trial looking at the use of hearing aids for cognitive decline has been published in The Lancet.   Dr Thomas Littlejohns, Senior Epidemiologist, Nuffield Department of Population Health,...

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expert reaction to unpublished conference abstract about olive oil and dementia

A conference abstract (not a published paper) presented at NUTRITION 2023 looks at olive oil intake and dementia risk.   Dr Duane Mellor, Registered Dietitian and Senior Lecturer, Aston Medical...

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expert reaction to observational study of particulate air pollution from...

An observational study published in JAMA Internal Medicine compares particulate air pollution from different emission sources and incident dementia in the US.   Prof Roy Harrison FRS, Professor of...

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expert reaction to study looking at whether navigational mistakes could be...

A study published in Current Biology looks at navigational mistakes as a possible sign of Alzheimer’s disease.    Dr Leah Mursaleen, Head of Research at Alzheimer’s Research UK, said: “There are...

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expert reaction to observational study of Tai Chi and Parkinson’s symptoms...

A study published in the Journal of Neurology, Neurosurgery and Psychiatry looks at the effect of long term Tai Chi training on the development of Parkinson’s disease.    Prof K Ray Chaudhuri,...

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expert reaction to study estimating dementia prevalence by 2040

A study published in Lancet Public Health looks at the dementia incidence trend in England and Wales.   Prof Marcus Richards, Professor of Psychology in Epidemiology, MRC Unit for Lifelong Health and...

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expert reaction to study of a neuroprosthesis for a man with Parkinson’s...

A study published in Nature Medicine looks at neuroprosthesis to improve mobility of people living with Parkinson’s Disease.    Prof David Dexter Director of Research, Parkinson’s UK, said: “This...

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Is a blood test for diagnosing Alzheimer’s on the horizon?

The way dementia is diagnosed has barely changed for nearly two decades, and here’s the shocker: at least a third of people who develop dementia never receive a diagnosis. But with the imminent...

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expert reaction to study claiming an association between very high levels of...

A study published in The Lancet Regional Health – Western Pacific looks at cholesterol levels and the risk of dementia.    Prof Tara Spires-Jones, President of the British Neuroscience Association,...

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